A Natural Alternative to Synthetic GLP-1 Injections
GLP THREE™ is a natural liquid formula designed to support your body's own metabolic pathways. No needles, no synthetic hormones, no prescription required.
Watch: GLP THREE™ In Action
A quick look at the natural approach behind GLP THREE™, before you dive into the details below.
Introducing GLP THREE™
A 100% natural formula for weight management and metabolic health, built around a patented peptide complex and three supporting plant extracts.
MBC-267 Peptides
A patented peptide complex found in salmon from the Norwegian Sea and in select mushrooms.
Panax Ginseng Extract
Rich in ginsenosides, a group of naturally occurring plant compounds.
Saffron Extract
Rich in safranal and crocin, compounds naturally found in saffron.
Humulus Lupulus Extract (Hops)
Rich in naturally occurring bitter acids.
How GLP THREE™ Works
The natural science behind cellular support and metabolic balance, without needles or synthetic hormones.
Natural GLP-1 Pathway Support
GLP THREE is formulated to naturally support your body's own GLP-1 pathway, the mechanism involved in signaling fullness after meals. Rather than introducing a synthetic hormone, the formula uses plant and marine-derived compounds intended to work with your existing biology.
Brain-Gut Communication
Supports the body's natural fullness signals after meals.
Cellular Absorption
Formulated for bioavailability so nutrients can reach cells.
Gentle Formula
Made with natural ingredients, not synthetic compounds.
Natural Appetite Support
GLP THREE is designed to support mindful eating by helping you feel satisfied with smaller portions and by supporting a reduction in cravings throughout the day.
Portion Support
Feel satisfied with less food, naturally.
Extended Satiety Support
Stay comfortably full longer between meals.
Craving Support
Supports a reduction in sugar and carbohydrate cravings.
Comprehensive Metabolic Support
GLP THREE is formulated to support more than appetite. It's designed to support blood sugar levels already within a normal range, support fat metabolism, and help maintain lean muscle as part of an active, balanced lifestyle.
Blood Sugar Support
Supports healthy glucose metabolism.
Fat Metabolism Support
Supports the body's natural fat-burning processes.
Muscle Preservation Support
Supports lean muscle as part of an active lifestyle.
Energy Support
Supports sustained energy through the day.
Natural GLP THREE™ vs. Synthetic Injections
A direct, factual comparison so you can decide what fits your life and your body.
| Feature | Natural GLP THREE™ | Synthetic Injections |
|---|---|---|
| Method | Easy liquid dropper. No needles, no injections. | Requires needles. Weekly or daily injections. |
| Formulation | Plant and marine-derived compounds. | Lab-created synthetic hormone. |
| Absorption | Formulated for bioavailability and effective cellular absorption. | Delivered directly into the bloodstream by injection. |
| Muscle Impact | Formulated to support lean muscle as part of an active lifestyle. | Rapid weight loss can include lean muscle tissue. |
| Digestive Tolerance | Digestive complaints common with synthetic options are not typically associated with natural ingredients like these. | Nausea and digestive discomfort are frequently reported. |
| Sustainability | Formulated for long-term use as part of a daily routine. | Weight regain is commonly reported after stopping. |
| Access | Available directly. No prescription required. | Requires a doctor's prescription, visits, and insurance approval. |
| Cost | $2894-bottle supply | $1,000+typical, per month |
Cost figures reflect typical reported pricing and are provided for comparison only. Individual results and costs vary. Talk to your doctor before starting any new supplement or changing a prescribed treatment.
The Science Behind GLP THREE™
Dr. Dan is a Caltech-trained Ph.D. in organic chemistry who has formulated more than 70 nutritional supplements, with 16 patents granted or pending. With over 15 years of formulation experience, his focus is on phytonutrients and cellular absorption.
Dr. Chris Colgin
Dr. Chris Colgin, of Optimal Health Members, has partnered with Three International to bring this natural formula to his community as an alternative to synthetic injections. Through Optimal Health Members, Dr. Colgin provides access to natural health solutions with a focus on safety and long-term wellness.
"GLP THREE is a natural option I'm comfortable recommending. It's formulated to work with the body, not against it."Dr. Chris ColginDirector, Optimal Health Members

Clinical Excellence

Scientific Innovation
Two Ways to Get Involved
Whether you want to start your own routine or help others find theirs, there's a path for you.
Start Your Transformation
Join those who have discovered the natural path to sustainable weight management and metabolic health with GLP THREE™.
- Third-party lab tested for purity and potency
- Gluten-free and non-GMO formula
- Personalized support with your consultation
Build Your Business
Become a brand ambassador and build a flexible, home-based business sharing a product you believe in.
- Home-based flexibility, work your own schedule
- Comprehensive training and support
- Residual income potential
No inventory required. Start today.
GLP THREE™, 4-Bottle Supply
Order 4 bottles of GLP THREE and receive a free consultation plus a computerized Body Composition Analysis with Dr. Chris Colgin.
- 4-bottle supply of GLP THREE™
- Free consultation with Dr. Chris Colgin
- Computerized Body Composition Analysis
You won't just get the product. You'll get a clear picture of your body, your progress, and your next steps.
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Get the Free Guide and Scientific Dossier
The Metabolism Fix: what actually drives stubborn weight gain, plus the full ingredient research behind GLP THREE, sent straight to your inbox.
- Why standard "eat less, move more" advice stops working for so many people
- The metabolic shifts most people never get told about
- The full ingredient profiles and research behind the formula
Send Me Both
No spam. Just the science and how GLP THREE fits in.
Frequently Asked Questions
Direct answers about the formula, how it compares, and what's included.
What is GLP THREE?
GLP THREE is a natural liquid supplement formulated to support metabolic health and weight management. It combines a patented MBC-267 peptide complex with Panax Ginseng, Saffron, and Hops extracts. It is not a prescription medication.
Is GLP THREE the same as Ozempic, Wegovy, or other GLP-1 injections?
No. GLP THREE does not contain semaglutide or any synthetic hormone. It is formulated with natural, plant and marine derived ingredients intended to support your body's own GLP-1 pathway. It is a natural alternative to synthetic injections, not a synthetic drug, and not a replacement for a prescribed medication without your doctor's guidance.
What is MBC-267?
MBC-267 (Metabolic Boost Complex-267) is a patented peptide complex identified in salmon from the Norwegian Sea and in select mushrooms. It is exclusive to Three International's formulation of GLP THREE.
How do I take GLP THREE?
GLP THREE is taken as an easy liquid dropper, with no needles or injections required. Follow the dosing instructions on the product label, and ask about guidance specific to you during your free consultation with Dr. Colgin's team.
Are there side effects?
GLP THREE is formulated with natural ingredients rather than a synthetic hormone. Digestive complaints commonly reported with synthetic injections are not typically associated with natural ingredients like these. Individual results and responses can vary, so talk to your physician before starting any new supplement.
Do I need a prescription to order GLP THREE?
No. GLP THREE is available directly, without a doctor's prescription or insurance approval.
How much does GLP THREE cost?
A 4-bottle supply of GLP THREE is $289 and includes a free consultation plus a computerized Body Composition Analysis with Dr. Chris Colgin. By comparison, synthetic GLP-1 injections typically cost $1,000 or more per month without insurance.
Can I become an ambassador and sell GLP THREE?
Yes. Three International offers a home-based ambassador program with no inventory required, comprehensive training, and residual income potential.
Recommended by
Dr. Chris Colgin
A natural path toward a leaner, healthier you, supported by real science and real guidance.
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